Stem rust is one of the most devastating diseases in cereals globally.
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New research helps combat devastating disease of wheat plants

A team of scientists have identified a promising resistance gene that could help fight a devastating fungus called stem rust, which attacks wheat crops and threatens global food security.

Stem rust, a virulent wheat disease caused by the fungus Puccinia graminis, has become a major threat to wheat crops in Africa and other regions. Breeders and farmers need access to more resistant germplasm (seeds) to protect wheat yields from losses due to disease epidemics, like the Ug99 strain which is attacking wheat crops in Africa and the Middle East.

Now a team of Australian and US American researchers have identified a resistance gene to fight stem rust. The discovery, published in Nature Plants in late July, also identifies a gene in the fungus that triggers this resistance in the host plant, and together these findings provide a pathway to help wheat growers defend against this disease.

Wheat provides roughly 20 per cent of calories and protein for human nutrition worldwide. Stem rust is among the world’s most devastating plant diseases, and can completely destroy a crop of wheat in a matter of weeks.

Dr Peter Dodds, Chief Research Scientist at Australia’s national science agency CSIRO, said this was yet another weapon in the armory to stay one step ahead of wheat stem rust globally. “Discovery of this resistance gene continues our effective collaboration with international partners that has already resulted in great advances to build resistance to this potentially devastating pathogen,” Dodds stressed.

One step closer to introducing multiple resistance genes into wheat

This new research will help researchers and wheat breeders to introduce multiple resistance genes into a wheat variety to build durable resistance to wheat rusts. This novel approach to providing durable resistance has been pioneered by CSIRO and the U.S.-based non-profit 2Blades Foundation, and is bolstered through a recent demonstration of a “gene stack” of five cloned Sr genes for effective stem rust resistance in wheat. The resulting new wheat variety shows exceptional resistance to stem rust.

Introducing a multi-gene stack is much more precise and quicker than conventional breeding, which can take decades to produce a wheat variety resistant to wheat rust diseases. This new method will also ensure that the desirable trait (determined by multiple genes) will not segregate and be lost in subsequent breeding.

The most effective and environmentally sound way to defend against wheat rust diseases is through the deployment of such resistance genes in wheat varieties. This is particularly important in developing countries, where the fungicides used to combat rust disease may be expensive or unavailable.


Peter N. Dodds et al.: Genomics accelerated isolation of a new stem rust avirulence gene–wheat resistance gene pair; Nature Plants, 22nd July 2021

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  • user
    Ibrahim July 2, 2023 At 10:56 am
    Very thank you